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Nonparenchymal Cells

The non parenchymal cells of the liver include populations of cholangiocytes (epithelial cells), sinusoidal endothelial cells, stellate cells, Kupffer cells, and intrahepatic lymphocytes. Combined they make up 40% of the cells in the liver.

The non-parenchymals produce key paracrine factors that influence growth, metabolism, and transport functions in hepatocytes.  Non-parenchymals can be primary targets for certain hepatotoxins and mediate physiological response of the liver to endocrine and immune signals.

Adding non-parenchymals  to your primary hepatocyte toxicity testing improves the physiological relevance of the results.

Name (click for details or to ORDER) Inventory
Human Nonparenchymals - H0045 (21 yr)

131

Human Nonparenchymals - H009275; passage 5 (progenitor source)

48

Human Nonparenchymals - H0109 (8 yr)

96

Human Nonparenchymals - H0165 (63 yr, diabetic Type II)

25

Human Nonparenchymals - H0965-A (neonate)

20

Human Nonparenchymals - H0965-B (neonate)

68

Human Nonparenchymals - H2329 B (14 yr)

5

Human Nonparenchymals - H928397 B (2 months)

469