Tissue Engineering
SciKon™ is an interdisciplinary Tissue Engineering company that integrates ‘Theories and Practices’ from a variety of scientific disciplines. SciKon merges engineering and biology efforts in support of clinical and pharmaceutical advancements. We pride ourselves on being experienced Liaisons in Biotechnology.
Our discoveries are formulated to better mimic natural in vivo tissue environments. Both acellular and cellular constructs are developed for broad-spectrum tissue phenotypes with unique correlations to organ demographics; especially from human heterogeneous donors.
Predictions
SciKon develops biotools maintained in controlled microenvironments for predictive life functions. We evolve micro-systems that allow our team to pioneer innovative human and animal biodesigns and devices into predictive model tools. For most cells, multiparameter ELISA profiles serve as a reference for interpretation of cell efficacy. These parameters provide evidence of the overall cell health. Associatively, HPLC and NMR metabolomic outcomes help define toxicodynamic and biokinetic models for acute and chronic cell testing and predictive modeling
Overall , SciKon’s mission is to provide innovation culture platforms, high quality primary cells, predictive model tools, and contract services to the biomedical research community.
Biodevice
Our mission is to improve medical and pharmaceutical biotools by exploiting engineering principles to include cell ecosystems, thermodynamics of living constructs, energy conservation, fluid transport & nutrient delivery, and ‘cells in systems’ approaches. We pioneer innovative human and animal cell culture devices into predictive model tools.
Our skills have developed to maintain ‘viable and functional’ human and animal tissues in varying microenvironments. For success, we align flow pressures and shear stressors with media volumes, nutrient capabilities, oxygen capacities, and thermo-fluid options.
Overall, a biodevice is only as good as its functional component, the cell. In the case of multiphysical systems, many cells.
Cell Culture
SciKon’s industrial and academic experiences are focused on bioengineered 2D and 3D environment-cell interactions. Our involvement includes human tissue procurement, primary cell development, bioreactor culture pharmaceutical trials, cryopreservation and cell thaw technology, and native “single organ” and “multi organ” in vitro co-culture systems.
For culture success, we associate cell receptor bonds with extracellular matrix (ECM) adaptations, nutrient capability, and oxygen concentrations in support of tissue efficacy. We amend mother natures’ native microenvironment design for the in vitro maintenance of cell health.